Glp-1-fc fusion protein formulation

Details Glp-1-fc fusion protein formulation Glp-1-fc fusion protein formulation

A - Human Necessities

61

K

A61K 9/08 (2006.01) A61K 38/26 (2006.01) A61K 47/26 (2006.01)

Patent

CA 2691695

The invention provides a stable solution formulation comprising a therapeutically effective amount of a GLP-1-Fc fusion protein at about pH 6.5 in citrate buffer with polysorbate-80 and mannitol. The formulation is useful in treating diabetes and obesity as well as a variety of other conditions or disorders.

L'invention concerne une formulation de solution stable comprenant une quantité thérapeutiquement efficace d'une protéine de fusion GLP-1-Fc à environ un pH 6,5 dans un tampon de citrate avec du polysorbate 80 et du mannitol. La formulation est utile pour traiter le diabète et l'obésité ainsi qu'une variété d'autres affections ou troubles.

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