Glp-1 fusion proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 38/26 (2006.01) A61K 38/38 (2006.01) A61P 3/10 (2006.01) C07K 14/605 (2006.01) C07K 14/765 (2006.01) C07K 19/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2434237

The present invention relates to glucagon-like-1 compounds fused to proteins that have the effect of extending the in vivo half-life of the peptides. These fusion proteins can be used to treat non-insulin dependent diabetes mellitus as well as a variety of other conditions.

La présente invention concerne des composés GLP-1 fusionnés à des protéines qui ont un effet de prolongation de la demi-vie in vivo des peptides. On peut utiliser ces protéines hybrides pour traiter le diabète non insulino-dépendant, ainsi qu'une diversité d'autres troubles.

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