Glucagon analogues

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/605 (2006.01)

Patent

CA 2747109

The invention provides materials and methods for promoting weight loss or preventing weight gain, and in the treatment of diabetes, metablic syndrome and associated disorders. In particular, the invention provides novel glucagon analogue peptides effective in such methods. The peptides may mediate their effect by having increased selectivity for the GLP-1 receptor as compared to human glucagon.

Linvention concerne des matériaux et des méthodes pour faciliter la perte de poids ou empêcher la prise de poids, et traiter le diabète, le syndrome métabolique et les troubles associés. Linvention concerne, en particulier de nouveaux peptides analogues du glucagon efficaces dans ces méthodes. Les peptides peuvent médier leur effet par leur sélectivité accrue pour le récepteur du GLP-1 par rapport au glucagon humain.

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