Glucagon-like insulinotropic complexes, compositions and...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/605 (2006.01) A61K 38/26 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2150080

The present invention provides novel complexes consisting of certain GLP-1 molecules associated with a divalent metal cation that is capable of co-precipitating with a GLP-1 molecule. Pharmaceutical compositions and methods of using such complexes for enhancing the expression of insulin in B-type islet cells is claimed, as is a method for treating maturity onset diabetes mellitus in mammals, particularly humans.

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