C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/605 (2006.01) A61K 38/22 (2006.01) A61K 38/26 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2160753
Glucagon-like insulinotropic peptide (GLP-1(7-37)) analogs and derivatives are disclosed. The analogs include amino acid substitutions, amino and carboxyl terminal modifications, and C6-C10 acylations. The claimed compounds stimulate the secretion or biosynthesis of insulin in poorly functioning beta cells and are therefore useful in treating Type II diabetics
Chen Victor John
Dimarchi Richard Dennis
Kriauciunas Aidas Vladas
Smiley David Lee
Stucky Russell Dean
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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