Glucagon - like peptide - 2 variants

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/16 (2006.01) A61K 38/26 (2006.01) A61P 1/00 (2006.01) C07K 14/065 (2006.01) C07K 14/605 (2006.01)

Patent

CA 2502324

The present invention relates to novel human glucagon-like peptide-2 (GLP-2) peptides and human glucagon-like peptide-2 derivatives which have a protracted profile of action due to increased resistance to degradation as well as polynucleotide constructs encoding such peptides, vectors and host cells comprising and expressing the polynucleotide, pharmaceutical compositions, uses and methods of treatment.

L'invention concerne de nouveaux peptides (GLP-2) peptide 2 du type glucagon, des dérivés de peptide 2 humain, du type glucagon, présentant un profil d'action prolongé, ainsi que des constructions de polynucléotide codant pour de tels peptides, des vecteurs et cellules hôtes comprenant et exprimant le polynucléotide, des compositions pharmaceutiques, des utilisations et des procédés de traitement.

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