Glucagon-like protein-1 receptor (glp-1r) agonist compounds

Details Glucagon-like protein-1 receptor (glp-1r) agonist compounds Glucagon-like protein-1 receptor (glp-1r) agonist compounds

C - Chemistry, Metallurgy

07

K

C07K 14/605 (2006.01) A61K 47/48 (2006.01) C07K 14/575 (2006.01)

Patent

CA 2674112

The present invention provides glucagon-like protein 1 receptor targeting compounds which, comprise glucagon-like protein 1 receptor targeting agent-linker conjugates linked to a combining site of an antibody. Various uses of the compounds are provided, including methods to prevent or treat diabetes or diabetes-related conditions.

La présente invention concerne des composés ciblant l'agoniste GLP-1R (GA) qui comprennent des conjugués agent-lieur ciblant l'agoniste GLP-1R qui sont liés à un site de combinaison d'un anticorps. L'invention concerne également diverses applications de ces composés, ainsi que des méthodes de prévention ou de traitement du diabète ou de troubles liés au diabète.

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