Glucoamylase variants with altered properties

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/34 (2006.01) C12N 1/15 (2006.01) C12N 15/56 (2006.01) C12N 15/80 (2006.01)

Patent

CA 2705941

The present disclosure relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present disclosure provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions and cleaning compositions. The disclosure also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.

La présente invention concerne des variants d'une glucoamylase parente qui possèdent des propriétés modifiées (par ex. une thermostabilité améliorée et/ou une activité spécifique). En particulier, la présente invention concerne des compositions qui comprennent des variants de glucoamylase, y compris des compositions hydrolysant l'amidon et des compositions de nettoyage. Elle concerne également des produits d'assemblage d'ADN qui codent pour lesdits variants, ainsi que des procédés de production des variants de glucoamylase dans des cellules hôtes.

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