Glucoamylase variants with altered properties

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/34 (2006.01) C07K 14/37 (2006.01) C12N 15/31 (2006.01) C12N 15/56 (2006.01) C12N 15/62 (2006.01)

Patent

CA 2665595

The present invention relates to variants of a parent glucoamylase having altered properties (e.g., improved thermostability and/or specific activity). In particular, the present invention provides compositions comprising the variant glucoamylases, including starch hydrolyzing compositions, animal feed compositions and cleaning compositions. The invention also relates to DNA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.

La présente invention concerne des variants d'une glucoamylase parente dotés de propriétés modifiées (par exemple, une thermostabilité améliorée et/ou une activité spécifique). La présente invention concerne en particulier des compositions contenant les variants de glucoamylase, notamment des compositions hydrolysant l'amidon, des compositions alimentaires pour animaux et des compositions de nettoyage. L'invention concerne également des constructions d'ADN codant pour les variants et des procédés de production des variants de glucoamylase dans des cellules hôtes.

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