Glucocerebroside treatment of disease

Details Glucocerebroside treatment of disease Glucocerebroside treatment of disease

A - Human Necessities

61

K

A61K 39/00 (2006.01) A61K 35/12 (2006.01) A61K 45/00 (2006.01) A61K 47/48 (2006.01) G01N 33/567 (2006.01)

Patent

CA 2540666

The present invention provides a method for the treatment of immune mediated or immune related diseases or disorders, infectious diseases, metabolic disorders and cancer in mammalian subjects. This method comprises the administration of a naturally occurring, mammalian intermediary metabolite or T cell receptor ligand, preferably a glucosylceramide, to a mammalian subject. In a preferred embodiment, such mammalian subjects are human beings.

La présente invention concerne une méthode pour le traitement de maladies ou d'affections médiées par le système immunitaire ou associées au système immunitaire, de maladies infectieuses, de troubles métaboliques et du cancer chez des sujets mammifères. Cette méthode consiste à administrer un métabolite intermédiaire naturel de mammifère ou un ligand du récepteur de lymphocytes T, de préférence un glucosylcéramide, à un sujet mammifère. Dans un mode de réalisation préféré, ces sujets mammifères sont des êtres humains.

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