C - Chemistry – Metallurgy – 07 – J
Patent
C - Chemistry, Metallurgy
07
J
C07J 41/00 (2006.01) A61K 31/575 (2006.01) A61P 5/46 (2006.01)
Patent
CA 2488535
This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin levels, or lipid levels, and/or decreasing body weight.
L'invention concerne de nouveaux composés qui sont des antagonistes de récepteurs glucocorticoïdes sélectifs du foie, des procédés de préparation de tels composés, et leurs procédés d'utilisation en matière de régulation du métabolisme, notamment pour abaisser les niveaux du glucose sérique, les niveaux d'insuline et/ou diminuer le poids corporel.
Bishop Richard D.
Gates Bradley D.
Jacobson Peer B.
Kym Philip R.
Lai Chunqiu
Karo Bio Ab
Sim & Mcburney
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