Glucocorticoid receptor modulators

Details Glucocorticoid receptor modulators Glucocorticoid receptor modulators

C - Chemistry, Metallurgy

07

D

C07D 401/02 (2006.01) A61K 31/185 (2006.01) A61K 31/40 (2006.01) A61K 31/44 (2006.01) A61K 31/445 (2006.01) A61K 31/496 (2006.01) A61K 31/5375 (2006.01) A61K 31/55 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) C07C 35/42 (2006.01) C07C 269/04 (2006.01) C07C 271/42 (2006.01) C07C 271/44 (2006.01) C07C 271/52 (2006.01) C07D 207/14 (2006.01) C07D 211/56 (2006.01) C07D 223/06 (2006.01) C07D 265/28 (2006.01) C07D 295/13 (2006.01) C07D 295/205 (2006.01) C07D 295/28 (2006.01)

Patent

CA 2360308

The present invention provides non-steroidal compounds of Formula I, and prodrugs and pharmaceutically acceptable salts thereof, which are selective modulators (e.g., agonists, partial agonists and antagonists) of a steroid receptor, specifically, the glucocorticoid receptor. The present invention also provides pharmaceutical compositions containing these compounds and methods for using these compounds to treat animals requiring glucocorticoid receptor agonist or antagonist therapy. Glucocorticoid receptor modulators are useful to treat diseases, such as obesity, diabetes, inflammation and others as described below. The present invention also provides processes for preparing these compounds.

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