Glucocorticoid-selective anti-inflammatory agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 491/04 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) C07D 221/00 (2006.01) C07D 239/00 (2006.01) C07D 311/00 (2006.01)

Patent

CA 2320943

Compounds having Formula (I), are useful for partially or fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of inhibiting immune or autoimmune diseases in a mammal.

Composés représentés par la formule (I) jouant un rôle utile partiel ou total d'antagonistes, de répresseurs, d'agonistes ou de modulateurs du récepteur de glucocorticoïdes et servant à traiter des maladies immunes, auto-immunes et inflammatoires chez le mammifère. Compositions pharmaceutiques contenant les composés ci-dessus et procédés permettant d'inhiber des maladies immunes ou auto-immunes chez le mammifère.

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