Glucocorticoid-selective anti-inflammatory agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 491/052 (2006.01) A61K 31/44 (2006.01) C07D 221/00 (2006.01) C07D 311/00 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2320911

Compounds having Formula (I) are useful for partially of fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor in a mammal and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of inhibiting immune or autoimmune diseases in a mammal.

On utilise des composés de formule (I) pour jouer le rôle, partiellement ou entièrement, de composés antagonistes, répresseurs, agonistes ou modulateurs du récepteur de glucocorticoïde chez un mammifère et pour traiter des maladies immunes, auto-immunes et inflammatoires chez un mammifère. On décrit également des compositions pharmaceutiques contenant les composés de formule (I) et des procédés d'inhibition de maladies immunes et auto-immunes chez un mammifère.

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