C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/04 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01)
Patent
CA 2415037
Compounds having formula I are useful for partially or fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of formula I and methods of inhibiting immune or autoimmune diseases in a mammal.
L'invention concerne des composés de formule I à utiliser comme antagonistes, répresseurs, agonistes ou modulateurs entiers ou partiels du récepteur de glucocorticoïde et dans le traitement de maladies immunes, auto-immunes et inflammatoires chez un mammifère. L'invention concerne également des compositions pharmaceutiques contenant ces composés de formule I ainsi que des procédés d'inhibition de maladies immunes ou auto-immunes chez un mammifère.
Coghlan Michael J.
Edwards James P.
Elmore Steven W.
Jones Todd K.
Kort Michael E.
Abbott Laboratories
Ligand Pharmaceuticals Incorporated
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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