Glucosamine derivative, process for preparing the same and...

Details Glucosamine derivative, process for preparing the same and... Glucosamine derivative, process for preparing the same and...

C - Chemistry, Metallurgy

07

H

C07H 15/04 (2006.01) A61K 31/70 (2006.01) C07H 15/12 (2006.01) C07H 15/18 (2006.01)

Patent

CA 2135536

Abstract: There are disclosed a D-glucosamine derivative represented by the formula (I): Image (I) wherein (1) X is a group of formula: Image and R1 and R2 are both hydrogen atoms; or (2) X is OH or a group of the formula: Image and one of R1 and R2 is a group of the formula: -Y-R11 or alkyl and the other is H, or one of R1 and R2 is a group of the formula: -Y-R11 and the other is alkyl; Y is a group of the formula: -CO-, -CS- or -SO2-; R11 is alkyl, lower alkoxy, alkenyl, alkynyl, phenyl, cyclo- alkyl, tricycloalkyl, heterocyclic or alkylamino; R3 is H, phenyl, phenoxy, phenylthio, phenylamino or heterocyclic; R4 is alkanoyl, alkenoyl or alkynoyl; and Alk is alkylene, provided that a compound in which X is OH, one of R1 and R2 is methyl and the other is acetyl is excluded, or a pharmaceutically acceptable salt thereof, a process for preparing the same, and a synthetic intermediate thereof.

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