C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/53 (2006.01) C12M 1/34 (2006.01) C12N 1/19 (2006.01) C12N 9/04 (2006.01) C12N 15/63 (2006.01) C12Q 1/32 (2006.01)
Patent
CA 2372741
A modified glucose dehydrogenase characterized in that, in water soluble glucose dehydrogenase accompanied by pyrrolo-quinoline quinone as a coenzyme, one or more amino acid residues in a specific region has been substituted by other amino acid residue(s). This modified PQQGDH has an improved affinity for glucose.
L'invention concerne une glucose-déshydrogénase modifiée qui se caractérise en ce que, dans une glucose-déshydrogénase hydrosoluble accompagnée de quinone de pyrrolo-quinoléine en tant que co-enzyme, un ou plusieurs restes d'acide aminé dans une zone spécifique ont été substitués par un ou plusieurs restes d'acide aminé. Ladite PQQGDH modifiée présente une affinité améliorée pour le glucose.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Sode Koji
Ultizyme International Ltd.
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