Glucuronate salt of a piperazine compound

Details Glucuronate salt of a piperazine compound Glucuronate salt of a piperazine compound

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/538 (2006.01) A61P 25/18 (2006.01)

Patent

CA 2620755

The present invention provides a salt form, and compositions thereof, useful as a modulator of one or more GPCRs and which exhibits desirable characteristics for the same. The present invention also provides methods for preparing said salt form, which is derived from 8-{4-[3-(5-fluoro- 1 H-indol-3- yl)-propyl] -piperazin- 1 -yl } -2-methyl-4H- benzo[l,4]oxazin-3-one and glucuronic acid.

L'invention concerne une forme saline, et des compositions de celle-ci, à utiliser pour moduler l'activité d'un ou de plusieurs récepteurs de type GPCR et qui présente des caractéristiques désirables. L'invention concerne également des procédés de préparation de ladite forme saline, qui est dérivée de 8-{4-[3-(5-fluoro-1H-indol-3-yl)-propyl]-pipérazin-1-yl}-2-méthyl-4H-benzo[l,4]oxazin-3-one, et d'acide glucuronique.

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