Glucuronide metabolites and epimers thereof of tigecycline

Details Glucuronide metabolites and epimers thereof of tigecycline Glucuronide metabolites and epimers thereof of tigecycline

C - Chemistry, Metallurgy

07

H

C07H 15/252 (2006.01) A61K 31/704 (2006.01) A61P 31/04 (2006.01) C07H 7/033 (2006.01)

Patent

CA 2586245

A glucuronide metabolite of tigecycline, and its corresponding epimer, have been identified in humans treated with tigecycline. Mass spectral data have been used to identify these structures.

L'invention porte sur un métabolite glucuronide de la tigecycline et sur son épimère correspondant, qui ont été identifiés chez des humains traités par la tigecycline. Des données spectrales de masse ont été utilisées pour identifier ces structures.

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