Glucuronyl c5-epimerase, dna encoding the same and uses thereof

Details Glucuronyl c5-epimerase, dna encoding the same and uses thereof Glucuronyl c5-epimerase, dna encoding the same and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/61 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/00 (2006.01) C12N 9/90 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2436728

The invention is directed to a novel purified mouse C5-epimerase, fragments thereof, nucleic acids encoding the same and the recombinant production thereof. The invention is also directed to fragments of such epimerase, especially N-terminal fragments that are useful in fusion protein constructs to enhance the activity of recombinantly-produced heterologous epimerase enzymes.

L'invention concerne une nouvelle C5-épimérase de souris purifiée, des fragments correspondants, des acides nucléiques codant pour cette épimérase et la production recombinante de celle-ci. L'invention se rapporte également à des fragments de cette épimérase, et notamment à des fragments N-terminaux utiles dans des constructions de protéines de fusion pour intensifier l'activité d'enzymes épimérases hétérologues produites par recombinaison.

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