C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/53 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) A61P 3/08 (2006.01) A61P 3/10 (2006.01) C07K 16/40 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12P 21/08 (2006.01) C12Q 1/48 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2412880
The present invention is drawn to a gene comprising a polynucleotide encoding a polypeptide composed of an amino acid sequence represented by SEQ ID NO: 1; a gene expression product produced through expression of the gene; a recombinant expression vector including the gene; a host cell (transformant) harboring the recombinant expression vector; a protein composed of an amino acid having an amino acid sequence represented by SEQ ID NO: 1; a therapeutic or preventive composition for hypoglycemia containing as an active ingredient the above-mentioned gene or protein; and an antibody capable of binding to the protein. Through use of the gene or an expression product thereof of the present invention, it is possible to elucidate the pathology of diabetes and develop drugs for treatment and prevention of diabetes via a new action mechanism.
L'invention concerne: un gène contenant un polynucléotide codant un polypeptide de la séquence d'aminoacides correspondant à SEQ ID NO:1; un produit d'expression génétique obtenu grâce à l'expression de ce gène; un vecteur d'expression de recombinaison comportant ce gène; une cellule hôte (transformant) portant ce vecteur; des compositions pour traiter ou prévenir l'hypoglycémie, lesquelles contiennent, comme principe actif, une protéine comprenant la séquence d'acides aminés correspondant au SEQ ID NO:1, le gène ou la protéine susmentionné(e); un anticorps pouvant se lier à la protéine décrite ci-dessus, etc. L'utilisation de ce gène et de son produit d'expression rendent possible la clarification d'états pathologiques dus au diabète, ainsi que le développement de médicaments, etc. pour la prévention ou le traitement du diabète fondé(e) sur un nouveau mécanisme fonctionnel.
Fujiwara Tsutomu
Kyushiki Hiroyuki
Niimi Masashi
Okamoto Takashi
Ueyama Atsunori
Gowling Lafleur Henderson Llp
Otsuka Pharmaceutical Co. Ltd.
LandOfFree
Glutamine fructose-6-phosphate amidotransferase splice... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Glutamine fructose-6-phosphate amidotransferase splice..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glutamine fructose-6-phosphate amidotransferase splice... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1824653