Glutamyl trna synthetase (gts) fragments

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 9/00 (2006.01) A61K 38/16 (2006.01) A61K 38/53 (2006.01) A61K 39/09 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2745205

The present invention relates to polypeptide fragments, including variants and analogs, of Streptococcus pneumonia (S. pneumoniae) glutamyl tRNA synthetase (GtS) protein and to vaccines comprising such polypeptide fragments. In particular, the present invention relates to the use of such vaccines for eliciting protective immunity to S. pneumoniae.

Linvention concerne des fragments de polypeptide comprenant des variants et des analogues de la protéine glutamyl-ARNt-synthétase (GtS) de Streptococcus pneumonia (S. pneumoniae) et des  vaccins comprenant ces fragments de polypeptide. Linvention concerne en particulier lutilisation des ces vaccins pour susciter une immunité protectrice contre S. pneumoniae.

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