Glyburide composition

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 311/59 (2006.01) A61K 31/64 (2006.01) A61P 3/10 (2006.01) A61K 9/14 (2006.01)

Patent

CA 2397294

The present invention relates to a physical form of the known drug substance glyburide, also known as glibenclamide, and chemically defined as 5-chloro-N-[2-[4-[[[(cyclcohexylamino)- carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxybenzamide (Merck Index, Tenth Edition, p.642), as well as to dosage forms, e.g., tablets and capsules, incorporating said physical form of glyburide.

L'invention concerne une forme physique de la substance médicamenteuse connue, le glyburide, également connue sous le nom de glibenclamide, laquelle correspond chimiquement à la formule suivante: 5-chloro-N-[2-[4-[[[(cyclohexylamino)-carbonyl]amino]sulfonyl]phényl]éthyl]-2méthoxybenzamide (Merck Index, dixième édition, p.642); elle concerne également des formes galéniques, par exemple des comprimés et des gélules, incorporant cette forme de glyburide.

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