A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01)
Patent
CA 2577999
The present invention relates to PEGylation of human Growth Hormone (hGH) using a glycerol branched PEG. The present invention also relates to processes for the PEGylation of hGH. In addition, the present invention relates to pharmaceutical compositions comprising the PEGylated hGH. A further embodiment is the use of the PEGylated hGH for the treatment of growth and development disorders.
La présente invention concerne la pégylation d'hormone de croissance humaine (hGH) au moyen d'un glycérol de PEG ramifié. La présente invention concerne aussi des processus de pégylation de hGH. Cette invention concerne aussi des compositions pharmaceutiques comprenant cette hormone de croissance humaine pegylatée. Un autre mode de réalisation de l'invention concerne l'utilisation de cette hormone de croissance humaine pegylatée destinée au traitement de troubles de la croissance et du développement.
Finn Rory F.
Siegel Ned R.
Pharmacia & Upjohn Company Llc
Smart & Biggar
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