Glycerol derivatives, their preparation and their...

Details Glycerol derivatives, their preparation and their... Glycerol derivatives, their preparation and their...

C - Chemistry, Metallurgy

07

D

260/302, 260/304

C07D 413/14 (2006.01) C07D 261/12 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07F 9/10 (2006.01) C07F 9/547 (2006.01) C07F 9/653 (2006.01) C07F 9/6539 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 1314889

ABSTRACT OF THE DISCLOSURE Glycerol derivatives having at least one heterocyclic group on the 3 or 2 position and a group of formula -Y-D-Q on the 1 position (in which Y represents oxygen, sulfur, -NR3-, -X-CO-R4-, -R4-CO-X-, -NR3-CO-, -CO-NR3- or -X-P(O)(OH)-O-, where -NR3- is optionally protected imino, R4 represents a direct bond or -NR3; and X represents oxygen or sulfur; D represents optionally substituted C1-C14 alkylene; and Q represents a nitrogen containing heterocyclic group or All amino group either or which is optionally quaternized) are PAF antagonists which may be used to treat asthma, inflammation and shock. They may be prepared by reacting a glycerol derivative having an active group at the 1-position with an appropriate compound to introduce the desired group.

529667

Affiliated with

Also associated with

Rating

Glycerol derivatives, their preparation and their... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Glycerol derivatives, their preparation and their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Glycerol derivatives, their preparation and their... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1172242