C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 9/117 (2006.01) A61K 31/683 (2006.01) A61P 17/00 (2006.01) A61P 19/00 (2006.01) A61P 25/00 (2006.01) A61P 27/00 (2006.01) A61P 31/00 (2006.01) C07F 9/10 (2006.01) C07F 9/177 (2006.01)
Patent
CA 2427352
Optionally O-substituted glycerol-phosphoinositol derivatives of the general formula (I) (see formula I) their analogues and their salts, pharmaceutical compositions comprising such compounds and use thereof for the treatment of pathologies mediated by activation or over-stimulation of cPLA2.
La présente invention concerne des dérivés de glycérophosphoinositol éventuellement substitués en O, leurs analogues, ainsi que leurs sels; les substituants R'1, R'2, R'3, R'4, R'5, R'6 étant tels que définis dans l'invention. L'invention concerne également la synthèse de ces dérivés ainsi que leur effet pharmacologique comme modulateurs de l'activation ou de la sur-stimulation de la cPLA2
Bonvento Giovanna
Corda Daniela
Dal Monte Renzo
Dal Toso Roberto
Marcolongo Gabriele
I.r.b. Istituto Di Ricerche Biotecnologiche S.r.l.
Robic
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