A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/683 (2006.01) A61K 31/685 (2006.01) A61P 3/10 (2006.01) A61P 9/10 (2006.01) A61P 15/12 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 25/22 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)
Patent
CA 2542504
Disclosed is a lipid preparation comprising a glycerophospholipid or salt, conjugate and derivatives thereof, particularly phosphatidylserine (PS), phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidyl-inositol (PI), phosphatidylglycerol (PG) and phosphatidic acid (PA), and poly- unsaturated fatty acid (PUFA) acyl groups, particularly long-chain poly- unsaturated fatty acid (LC-PUFA) acyl groups such as omega-3 and/or omega-6 acyl groups, wherein said PUFA is covalently bound to said glycerophospholipid. The disclosed preparations possess an improved bioactivity, and are useful in the treatment of various cognitive and mental conditions and disorders and for maintenance of normal functions of brain- related systems and processes, for example ADHD.
L'invention concerne une préparation de lipides comprenant un glycérophospholipide, ou un sel, un conjugué et des dérivés de celui-ci, en particulier la phosphatidylsérine (PS), la phosphatidylcholine (PC), la phosphatidyléthanolamine (PE), le phosphatidyl-inositol (PI), le phosphatidylglycérol (PG) et l'acide phosphatidique (PA), et des groupes acyle d'acides gras polyinsaturés (PUFA), en particulier des groupes acyle d'acides gras polyinsaturés à longue chaîne (LC-PUFA) tels que des groupes acyle oméga-3 et/ou oméga-6, ledit PUFA étant lié de façon covalente au glycérophospholipide. Les préparations décrites présentent une activité biologique améliorée et sont utiles dans le traitement de diverses affections cognitives et mentales, et pour l'entretien de fonctions normales de systèmes et de processus liés au cerveau.
Bar-On Zohar
Ben Dror Gai
Farkash Orly
Pelled Dori
Plat Dorit
Enzymotec Ltd.
Oyen Wiggs Green & Mutala Llp
LandOfFree
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