Glycine derivative and preparation thereof

C - Chemistry – Metallurgy – 07 – C

Patent

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167/246, 530/5,

C07C 311/19 (2006.01) A61K 31/195 (2006.01) A61K 38/05 (2006.01) C07C 311/18 (2006.01) C07K 5/062 (2006.01)

Patent

CA 2004883

ABSTRACT OF DISCLOSURE: Novel glycine derivative having the formula (I): Image (I) wherein R1 is a substituted or unsubstituted phenyl group; either R2 or R3 is a lower alkyl group and the other is hydrogen atom, R4 is a protected or nonprotected carboxyl group, Q is a lower alkylene group and m is 0 or or a pharmaceutically acceptable salt thereof are disclosed. Said derivative (I) and a pharmaceutically acceptable salt thereof have a potent platelet aggregation-inhibiting activity.

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