C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/34 (2006.01) A61K 31/335 (2006.01) A61K 31/351 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61P 1/00 (2006.01) A61P 1/12 (2006.01) A61P 29/00 (2006.01) C07D 239/42 (2006.01) C07D 239/46 (2006.01) C07D 239/47 (2006.01) C07D 239/52 (2006.01) C07D 239/60 (2006.01) C07D 309/10 (2006.01) C07D 313/04 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 417/12 (2006.01)
Patent
CA 2592170
A glycine derivative which is, e.g., the following compound (Chemical formula (1)). It is highly effective in the treatment and prevention of inflammatory bowel diseases. Compared to conventional compounds, the compound is excellent in absorbability in oral administration and in vivo stability. The compound can be orally administered and can retain an excellent therapeutic or preventive effect over a longer period.
La présente invention concerne un dérivé de la glycine qui est, par exemple, le composé suivant (Formule chimique (1)). Il est hautement efficace dans le traitement et la prévention des troubles intestinaux inflammatoires. Comparé aux composés classiques, le composé est excellent en termes de capacité d~absorption en cas d~administration orale et de stabilité in vivo. Le composé peut être administré par voie orale et peut conserver un excellent effet thérapeutique ou préventif sur une plus longue période.
Hara Sunao
Hayashi Kenichi
Hirano Noriyuki
Inoue Hideki
Kaino Mie
Smart & Biggar
Toray Industries Inc.
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