Glycine transport inhibitors

Details Glycine transport inhibitors Glycine transport inhibitors

Category

C - Chemistry, Metallurgy

Subcategory

07

Subsubcategory

D

IPC codes

C07D 487/04 (2006.01) A61K 31/445 (2006.01) A61K 31/451 (2006.01) A61K 31/4523 (2006.01) A61K 31/495 (2006.01) A61K 31/519 (2006.01) A61K 31/55 (2006.01) C07D 211/14 (2006.01) C07D 211/18 (2006.01) C07D 211/22 (2006.01) C07D 211/30 (2006.01) C07D 211/34 (2006.01) C07D 211/58 (2006.01) C07D 211/88 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/12 (2006.01) C07D 405/06 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 4

Type

Patent

Patent number

CA 2322136

Description

The present invention is concerned with the use of glycine transport inhibiting .alpha.,.alpha.-diphenyl-1-piperidinebutanamides for the preparation of medicaments for treating disorders of the central and peripheral nervous system, in particular psychoses, pain, epilepsy, neurodegenerative diseases (Alzheimer's disease), stroke, head trauma, multiple sclerosis and the like. The invention further comprises novel compounds, their preparation and their pharmaceutical forms.

La présente invention concerne l'utilisation des .alpha.,.alpha.-diphényl-1-pipéridinebutanamides, inhibiteurs du transport de la glycine, pour la préparation de médicaments destinés aux traitements des troubles du système nerveux périphérique et du système nerveux central, en particulier, des psychoses, de la douleur, de l'épilepsie, des maladies neurodégénératives (maladie d'Alzheimer), de l'ictus, du trauma crânien, de la sclérose multiple et des troubles de même genre. La présente invention concerne aussi de nouveaux composés, leur préparation et leurs formes galéniques.

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