Glycogen synthase kinase-3 inhibitors

Details Glycogen synthase kinase-3 inhibitors Glycogen synthase kinase-3 inhibitors

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 25/18 (2006.01) A61P 25/24 (2006.01) A61P 25/28 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C12N 9/12 (2006.01) C12Q 1/48 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2509374

Novel conjugates that are capable of inhibiting GSK-3 activity, a process of producing same, pharmaceutical compositions including same and methods of using same in the treatment of GSK-3 mediated conditions are disclosed. Methods of treating affective disorders using GSK-3 inhibitors are further disclosed.

La présente invention se rapporte à de nouveaux conjugués qui sont capables d'inhiber l'activité de la glycogène synthase kinase-3 (GSK-3), à un procédé de production de ces nouveaux composés, à des compositions pharmaceutiques les contenant et à des procédés d'utilisation de ces conjugués pour le traitement d'états pathologiques médiés par la GSK-3. L'invention se rapporte également à des méthodes de traitement des troubles affectifs au moyen d'inhibiteurs de la GSK-3.

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