Glycoisoforms of adiponectin and uses thereof

Details Glycoisoforms of adiponectin and uses thereof Glycoisoforms of adiponectin and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 14/575 (2006.01) A61K 38/22 (2006.01) A61P 3/00 (2006.01) C07K 14/47 (2006.01) C07K 16/26 (2006.01) C12N 5/16 (2006.01) C12Q 1/02 (2006.01) G01N 33/74 (2006.01) C07K 14/78 (2006.01)

Patent

CA 2473781

Adiponectin polypeptide (particularly those glycosylated pereferably at lysine sites 65, 68, 77 and 101 and corresponding to the human adiponectin and particulary those hydroxylated at the praline 91) have been shown to be effective for the treatment of a range of condisions. Related compositions, uses and methods are disclosed.

L'invention concerne le polypeptide adiponectine (en particulier avec glycosylation de préférence aux sites de lysine 65, 68, 77 et 101, et correspondant à l'adiponectine humaine, et en particulier avec hydroxylation en praline 91), qui a montré son efficacité pour le traitement d'une série d'affections. L'invention concerne également des compositions, des utilisations et des procédés connexes.

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