Glycolic acid platinum complexes

Details Glycolic acid platinum complexes Glycolic acid platinum complexes

C - Chemistry, Metallurgy

07

F

260/429.4, 260/2

C07F 15/00 (2006.01) C07C 51/41 (2006.01) C07C 59/06 (2006.01)

Patent

CA 1186307

ABSTRACT OF THE DISCLOSURE Novel water-soluble glycolic acid platinum complexes which have more potent antitumor activity with lower nephrotoxicity than cisplatin does are provided. They can be administered parenterally to patients attacked by malignant tumors, Prepared from dinitrato-platinum complexes of amines on treatment with anion exchange resins and subsequent reaction with glycolic acid.

443806

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