Glycolide production process, and glycolic acid oligomer for...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 319/12 (2006.01)

Patent

CA 2440379

The invention relates to a glycolide production process wherein a depolymerization reaction system comprising a glycolic acid oligomer or a glycolic acid oligomer and a polar organic solvent is heated to depolymerize the glycolic acid oligomer into glycolide, the resulting glycolide or the glycolide and polar organic solvent are distilled out of the depolymerization reaction system, and the glycolide is recovered from distillates obtained by distillation. The glycolic acid oligomer or the glycolic acid oligomer and polar organic solvent are continuously or intermittently charged into the depolymerization reaction system, thereby carrying out depolymerization reactions continuously or repeatedly. During the depolymerization reactions, a compound having an alcoholic hydroxyl group is permitted to exist at a specific quantitative ratio in the depolymerization reaction system. The invention is also concerned with a glycolic acid oligomer for the production of glycolide, which is obtained by condensation of glycolic acid in the presence of the compound having an alcoholic hydroxyl group.

La présente invention concerne un procédé de production de glycolide dans lequel un système de réaction de dépolymérisation, comprenant un oligomère d'acide glycolique ou un oligomère d'acide glycolique et un solvant organique polaire, est chauffé pour dépolymériser l'oligomère d'acide glycolique en glycolide, le glycolide ou le glycolide et le solvant organique polaire étant obtenus par distillation du système de réaction de dépolymérisation, et le glycolide est récupéré des distillats obtenus par distillation. L'oligomère d'acide glycolique ou l'oligomère d'acide glycolique et le solvant organique polaire sont chargés en continu ou de façon successive dans le système de réaction de dépolymérisation, permettant ainsi des réaction de dépolymérisation en continu ou de façon répétée. Au cours des réactions de dépolymérisation, un composé possédant un groupe hydroxyle alcoolique peut exister selon un rapport quantitatif spécifique dans le système de réaction de dépolymérisation. L'invention concerne également un oligomère d'acide glycolique permettant la production de glycolide, qui est obtenu par condensation d'acide glycolique en présence du composé possédant un groupe hydroxyle alcoolique.

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