Glycoloyl-substituted oxazolidinone-derivatives as...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/10 (2006.01) A61K 31/454 (2006.01) A61K 31/496 (2006.01) A61P 31/04 (2006.01) C07D 263/20 (2006.01)

Patent

CA 2490193

The present invention describes difluororthioacetamide oxazolidinones_of formula I with a glycoloylpiperazine substituent as novel antibacterial agents, and antimicrobial combination therapies for combatting infective diseases caused by gram-positive and gram-negative bacteria.

L'invention concerne des difluororthioacétamides d'oxazolidinones de formule I comprenant un substituant glycoloylpiperazine et utilisés comme nouveaux agents anti-bactériens, ainsi que des polythérapies anti-microbiennes permettant de combattre des maladies infectieuses induites par des bactéries à gram positif et à gram négatif.

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