Glycopeptide antibiotic derivatives

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 9/00 (2006.01) A61K 38/14 (2006.01) A61P 31/04 (2006.01) C07K 1/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2216167

The present invention provides glycopeptide antibiotic derivative compounds. These derivative compounds possess antibacterial activity against a wide variety of bacteria, including activity against vancomycin-resistant isolates. Methods of making and using these glycopeptide antibiotic derivative compounds are also provided.

La présente invention se rapporte à des composés dérivés d'antibiotiques à base de glycopeptides. Ces composés dérivés possèdent une activité antibactérienne contre une large variété de bactéries, y compris une activité contre des isolats résistant à la vancomycine. Les méthodes de fabrication et d'utilisation de ces composés dérivés d'antibiotiques à base de glycopeptides sont également décrites.

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