Glycopeptide antibiotics

C - Chemistry – Metallurgy – 12 – N

Patent

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530/9, 195/1.34,

C12N 1/20 (2006.01) A61K 38/08 (2006.01) C07K 9/00 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2027629

Newly discovered lipoglycopeptide antibiotic A84575 complex, comprising factors A, B, C, D, E, F, G, and H, is produced by submerged aerobic fermentation of a culture selected from Streptosporangeum carneum NRRL 18437, Streptosporangeum carneum NRRL 18505 or an A84575-producing mutant thereof. The antibiotics are active against Gram-positive bacteria.

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