Glycopeptide derivatives and pharmaceutical compositions...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 9/00 (2006.01) A61K 38/00 (2006.01) A61K 38/14 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2336445

Disclosed are derivatives of glycopeptide compounds having at least one substituent of the formula: -Ra-Y-Rb-(Z)x where Ra, Rb, Y, Z and x are as defined, and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.

L'invention concerne des dérivés de composés de glycopeptide comportant au moins un substituant de la formule -R?a¿-Y-R?b¿-(Z)¿x? dans laquelle R?a¿, R?b¿, Y et Z sont tels que définis. En outre, l'invention a pour objet des compositions pharmaceutiques contenant ces dérivés. Ces derniers présentent un grand intérêt comme agents antibactériens.

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