Glycopeptide hexapeptides

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/12 (2006.01) C07K 5/00 (2006.01) C07K 7/00 (2006.01) C07K 9/00 (2006.01) C07K 16/00 (2006.01) C07K 17/00 (2006.01)

Patent

CA 2290724

The present invention is directed to glycopeptides and more particularly to derivatives of the glycopeptide A82846B. In these derivatives, the leucyl has been removed to create "hexapeptides" of A82846B and its N DISACC variations. These hexapeptides are useful as antibacterials and also as starting materials from which further antibacterial compounds are prepared.

L'invention décrit des glycopeptides et plus particulièrement des dérivés du glycopeptide A82846B. Dans ces dérivés, on a retiré le leucyle pour produire des "hexapeptides" de A82846B et les variations N<DISACC> de ce dernier. Ces hexapeptides sont utiles comme antibactériens ainsi que comme matières premières pour préparer d'autres composés antibactériens.

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