Glycoproteinic conjugates having trivalent immunogenic activity

Details Glycoproteinic conjugates having trivalent immunogenic activity Glycoproteinic conjugates having trivalent immunogenic activity

A - Human Necessities

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A61K 39/116 (2006.01) A61K 39/385 (2006.01) C07K 15/14 (1985.01)

Patent

CA 1272952

"GLYCOPROTEINIC CONJUGATES HAVING TRIVALENT IMMUNOGENIC ACTIVITY" Abstract of the Disclosure Glycoproteinic conjugates having trivalent immuno- genic activity obtained by binding, by a covalent bond, to a protein selected among CRM 197, tetanus toxoid, and pertussis toxin, at least an oligosaccharidic hapten derived from the capsular polysaccharide of a gram-posi- tive bacterium and at least an oligosaccharidic hapten derived from the capsular polysaccharide of a gram-nega- tive bacterium, and wherein said oligosaccharidic haptens are previously activated by introducing terminal esters.

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