Glycoproteins, process for preparation thereof, and...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 14/375 (2006.01) A61K 38/16 (2006.01) C12P 21/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2168827

A glycoprotein which is prepared by chemically treating an extract from mycelium, broth or fruit body of a fungus belonging to Coriolus, and has following physicochemical properties: a molecular weight determined by gel chromatography being 5,000 to 1,000,000; a ratio (proteins/sugars) of an amount of proteins determined by Lowry-Folin method to an amount of sugars determined by phenol-sulfate method being 0.7 to 5.0; and 1?3 glucan accounting for 18 to 100 % in glucans in sugars is disclosed. The glycoprotein is effective to a malignant tumor, or a disease which an immune system or a growth factor is implicated in.

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