Glycosaminoglycan-modified protein

Details Glycosaminoglycan-modified protein Glycosaminoglycan-modified protein

C - Chemistry, Metallurgy

07

K

167/103, 530/17.

C07K 17/10 (2006.01) A61K 38/16 (2006.01) A61K 47/48 (2006.01) C07K 1/107 (2006.01) C08B 37/00 (2006.01) C12N 9/96 (2006.01) C12N 11/10 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2027447

ABSTRACT OF THE DISCLOSURE A glycosaminoglycan-modified protein wherein an amino group of a protein is bound to an aldehyde group, which has been formed by reducing and partially oxidizing the reducing terminal sugar moiety of a glycosaminoglycan, which has a high stability in vivo and can retain physiological activity of the protein for a prolonged period of time.

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