Glycosaminoglycans having high antithrombotic activity

Details Glycosaminoglycans having high antithrombotic activity Glycosaminoglycans having high antithrombotic activity

C - Chemistry, Metallurgy

08

B

C08B 37/00 (2006.01) C08B 37/10 (2006.01) A61K 31/725 (1995.01)

Patent

CA 2285383

Glycosaminoglycans having high antithrombotic activity in vitro, obtained by various kinds of glycosaminoglycans supersulfated by the preparation of the salt of an organic base of the starting supersulfated glycosaminoglycan, by partial solvolithic desulfation of said salt and N-resulfation of said partially desulfated product.

Glycosaminoglycanes présentant une efficacité élevée in vitro contre la thrombose, obtenus à partir de différentes sortes de glycosaminoglycanes sursulfatés par la préparation du sel d'une base organique du glycosaminoglycane sursulfaté de départ, par désulfatation solvolithique partielle dudit sel et N-resulfatation dudit produit partiellement désulfaté.

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