A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/704 (2006.01) A61K 9/127 (2006.01) A61K 31/7032 (2006.01) A61K 47/18 (2006.01) A61K 47/24 (2006.01) A61P 35/00 (2006.01) C07H 15/10 (2006.01) C07H 15/18 (2006.01) C07J 17/00 (2006.01)
Patent
CA 2529992
A drug product which can maximize the effect of a cholestanol glycoside useful as an anticancer agent. The present invention provides a liposomal composition containing a glycoside exhibiting antitumor activity, a phospholipid, and a positive-charge-providing substance; the glycoside being composed of GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, or Gal- as a sugar moiety, and a hydrophobic compound capable of forming a liposome.
L'invention concerne une préparation médicale pouvant maximiser l'effet d'un glycoside cholestanol utile en tant qu'agent antitumoral. Il s'agit d'un liposome qui contient : un glycoside à composé hydrophobe comportant une activité antitumorale, qui contient du GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc ou Gal- en tant que sucre, et permettant de former un liposome; un phospholipide; et une substance offrant une charge positive.
Nishimura Touyou
Takai Izumi
Yazawa Shin
Gowling Lafleur Henderson Llp
Otsuka Pharmaceutical Co. Ltd.
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