C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/228, 150/15.
C07D 265/38 (2006.01) C07D 265/36 (2006.01) C07H 17/00 (2006.01) C12Q 1/34 (2006.01) C12Q 1/54 (2006.01)
Patent
CA 1257253
ABSTRACT Glycosides of resorufin derivatives, processes for the preparation thereof and the use thereof for determining the activities of glycosidases The present invention provides glycosides of resorufin derivatives of the general formulae:- Image (Ia) Image (Ib) wherein R is a hydrogen atom, R2, R3 and R5, which can be the same or different, are hydrogen or halogen atoms or lower alkyl radicals, R4 and R6, which can be the same or different, are hydrogen or halogen atoms, cyano groups, lower alkyl, lower alkoxy, carboxyl, lower alkoxycarbonyl, carboxy lower alkyl or lower alkoxycarbonyl lower alkyl radicals or carboxamido groups optionally substituted once or twice or radicals of the general formula -COO-(CH2CH2O)n-R7, wherein R7 is a hydrogen atom or a lower alkyl radical and n is a whole number from 1 to 4, and R6 can additionally also represent a sulphonyl or nitro group and Y is a nitrogen atom or the group N ? 0. The present invention also provides processes for the preparation of these glycosides and diagnostic agents containing them. Furthermore, the present invention provides starting materials for the preparation of these glycosides.
477854
Batz Hans-Georg
Hofmann Jurgen
Klein Christian
Sernetz Manfred
Boehringer Mannheim G.m.b.h.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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