Glycosylated amino acids and peptides

Details Glycosylated amino acids and peptides Glycosylated amino acids and peptides

C - Chemistry, Metallurgy

07

K

167/199, 260/228

C07K 9/00 (2006.01) A61K 31/70 (2006.01) A61K 38/14 (2006.01) C07H 15/00 (2006.01) C07K 1/02 (2006.01)

Patent

CA 1338500

The invention relates to compounds of the formula I Image ( I) in which R1 represents methyl or CH2-OR2, R2 represents hydrogen, a protective group customary in carbohydrate chemistry, or a mono-, di- or trisaccharide, A represents a hydroxy amino acid, X represents hydrogen, halogen, N3 or (subst.)amino, Y represents hydrogen, a urethane protective group or an amino acid or a peptide, W represents hydroxyl, a carboxyl protective group or an amino acid or a peptide, or Y and W together with A re- present a cyclopeptide. These compounds contain a maximum of 20 amino acids. A process for the preparation thereof, and the use thereof, are also described.

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