Glycosylated steroid derivatives with anti-migratory activity

Details Glycosylated steroid derivatives with anti-migratory activity Glycosylated steroid derivatives with anti-migratory activity

C - Chemistry, Metallurgy

07

J

C07J 7/00 (2006.01) A61K 31/57 (2006.01) A61K 31/575 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2549074

The present invention relates to novel glycosylated steroid compounds having anti-migratory activity. The present invention also relates to a method for the preparation of said glycosylated steroid compounds. The invention further relates to a pharmaceutical composition comprising an effective amount of said glycosylated steroid compounds. Furthermore, the present invention concerns the use of said glycosylated steroid compounds as a medicament and in the preparation of a medicament for the treatment of diseases associated with cell migration, and even in particular in the treatment of cancer. The present invention also relates to the use of a glycosylated steroid compound or a pharmaceutical composition comprising said glycosylated steroid compound according to the invention in the treatment of diseases associated with cell migration, and even in particular in the treatment of cancer.

Cette invention concerne de nouveaux composés stéroïdes glycosylés présentant une activité anti-migratoire. Cette invention concerne également un procédé de préparation de ces composés stéroïdes glycosylés, une composition pharmaceutique comprenant une quantité efficace de ces composés stéroïdes glycosylés, ainsi que l'utilisation de ces composés stéroïdes glycosylés d'une part comme médicament et d'autre part dans la préparation d'un médicament servant au traitement de maladies associées à la migration cellulaire et en particulier dans le traitement du cancer. Cette invention concerne en outre l'utilisation du composé stéroïde glycosylé ou de la composition pharmaceutique renfermant le composé stéroïde glycosylé de cette invention dans le traitement de maladies associées à la migration cellulaire et en particulier dans le traitement du cancer.

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