A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7032 (2006.01) A61K 39/02 (2006.01) A61K 39/09 (2006.01) A61K 39/095 (2006.01) A61K 39/102 (2006.01) A61K 39/39 (2006.01) A61K 47/48 (2006.01) A61P 37/04 (2006.01)
Patent
CA 2579488
The invention provides compositions and kits comprising: (a) a saccharide antigen conjugated to a carrier; and (b) an alpha-glycosylceramide adjuvant. The invention further provides uses of the compositions. It has been found that suppression of anti-saccharide immune responses by alpha- glycosylceramides can be reversed by conjugating the saccharide to a carrier.
La présente invention concerne des compositions et des kits comprenant : (a) un antigène de saccharide conjugué à un support ; et (b) un adjuvant de a-glycosylcéramide. L'invention a également pour objet des procédés de traitement employant ces compositions. Il a été démontré que la suppression de réponses immunitaires anti-saccharide, par des a-glycosylcéramides, peut être inversée par conjugaison du saccharide à un support.
Borden Ladner Gervais Llp
Novartis Vaccines And Diagnostics Srl
LandOfFree
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