Glycyrrhizin preparations for transmucosal absorption

Details Glycyrrhizin preparations for transmucosal absorption Glycyrrhizin preparations for transmucosal absorption

A - Human Necessities

61

K

A61K 31/704 (2006.01) A61K 9/00 (2006.01) A61K 9/02 (2006.01) A61K 9/06 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61K 9/52 (2006.01) A61K 47/14 (2006.01) A61P 1/02 (2006.01) A61P 1/16 (2006.01) A61P 17/00 (2006.01) A61P 17/14 (2006.01) A61P 31/18 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2379313

By blending glycyrrhizin with an ester mixture comprising a C6-18 fatty acid glycerol ester with a C6-18 fatty acid macrogol ester, glycyrrhizin can be efficiently absorbed via mucosae (in particular digestive mucosae) to achieve a therapeutically effective plasma glycyrrhizin level.

En mélangeant la glycyrrhizine avec un mélange d'esters contenant un C¿6-18? ester de glycérol d'acide gras avec un C¿6-18? ester de macrogol d'acide gras, la glycyrrhizine peut être absorbée efficacement par voie muqueuse (particulièrement la muqueuse digestive) pour obtenir un taux de glycyrrhizine plasmique efficace sur le plan thérapeutique.

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