Gm-95-containing antitumor effect potentiator, combined...

A - Human Necessities – 61 – K

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A61K 31/429 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01) C07D 513/22 (2006.01)

Patent

CA 2517850

An antitumor effect potentiator for an antitumor substance which contains a compound represented by the following general formula (1) or its pharmaceutically acceptable salt: (1) wherein R~s independently represent each hydrogen, lower alkyl, aryl, allyl, aralkyl, halogeno, hydroxy, amino, R~O-, R~(C=O)-, R~(C=O)O- or R~O(C=O)-, wherein R~ is C1-5 alkyl.

La présente invention a trait à un agent de potentialisation pour une substance antitumorale qui contient un composé de formule générale (1), dans laquelle : les R représentent chacun, indépendamment les uns des autres, hydrogène, alkyle inférieur, aryle, allyle, aralkyle, halogéno, hydroxy, amino, R'O-, R'(C=O)-, R'(C=O)O- ou R'O(C=O)-, où R' est un alkyle en C¿1?-C¿5 ?; ou un de ses sels pharmaceutiquement acceptable.

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